BAYLOR COLLEGE OF MEDICINE IT 2016 DRIVER
The potential driver mutations spanned a broad spectrum of genes previously implicated not only in pediatric cancers, but also in adult cancers. Congratulations Class of 2016 Match Day 2016 Photos Match Day 2016 Story Name Specialty Program Name and Location Azka Afzal Internal Medicine Baylor. Using genomic technology to analyze both tumor and blood samples from a large number of children who’d been newly diagnosed with cancer, an NIH-funded research team uncovered genetic clues with the potential to refine diagnosis, identify inherited cancer susceptibility, or guide treatment for nearly 40 percent of the children. Baylor College of Medicine has established the College’s first-ever rural health residency program and will welcome the first set of residents in. And, as a new study shows, this approach even appears to have potential to help cancer’s littlest victims. We are now learning that it may be far more important for treating cancer to figure out what driver mutations are present in a patient’s tumor than to identify in which organ it arose. Most are DNA copying errors of no significance (we call those “passengers”), but a few of them occur in genes that regulate cell growth and contribute causatively to the cancer (we call those “drivers”).
As the technology for sequencing cancer genomes has advanced, we are learning that virtually all cancers carry a unique set of mutations. One of the most profound is the realization that cancer is a disease of the genome, driven by a wide array of changes in DNA-some in the germline and affecting all cells of the body, but most occurring in individual cells during life (so-called “somatic mutations”). 2Center for Medical Ethics and Health Policy, Baylor College of Medicine. Main academic topics: Medicine, Biology, and Psychology. 5Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 6Augsburg College. Kuntz/Texas Children’s HospitalĪn impressive number of fundamental advances in our understanding of cancer have occurred over the past several decades. The Baylor College of Medicine has an acceptance rate of 4, enrollment - 1,586, male/female ratio - 43:57, founded in 1900.
Caption: Baylor’s Sharon Plon consults with a family at the Texas Children’s Cancer Center in Houston.Ĭredit: Paul V.
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